Medulloblastoma: Mutations In Childhood Brain Tumors Identified

Sunday, July 22, 2012 - 16:10 in Health & Medicine

Researchers have linked mutations in specific genes to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children. The discovery provides doctors with potential biomarkers for guiding and individualizing treatment and reveals prospective therapeutic opportunities for countering this devastating malignancy.Medulloblastomas occur in the cerebellum, the part of the brain that controls balance and other complex motor functions, and are treated with a combination of surgery, radiation and chemotherapy. Though overall survival hovers around 70 percent, most survivors are unable to live independently due to the lasting effects of both tumor and treatment.  read more

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