Discovery: New PNPASE Role In Shuttling RNA Into Mitochondria
Friday, August 6, 2010 - 09:14
in Biology & Nature
In a new Cell study, researchers say they have uncovered a new role for an essential cell protein polynucleotide phosphorylase (PNPASE) in shuttling RNA into the mitochondria, the energy-producing 'power plant' of the cell. The import of nucleus-encoded small RNAs into mitochondria is essential for the replication, transcription and translation of the mitochondrial genome, but the mechanisms that deliver RNA into mitochondria remain poorly understood. read more