Friction And Epistasis: You Can't Ignore 'em

Wednesday, April 14, 2010 - 22:42 in Biology & Nature

Personalized genetics is hot in the news right now, but in fact we're generally terrible at using genotypes to predict who is going to get a disease. One villain here is the phenomenon known as epistasis, which essentially means that the physiological effect of one genetic variant depends on what other genetic variants (in other genes) are hanging around in the same genome. read more

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