[In Depth] Unexpected revelations for study volunteer
About 5 years ago, psychologist Rita Woidislawsky joined a research study studying people with naturally elevated high-density lipoprotein (HDL) cholesterol, sometimes called "good" cholesterol. Like millions of volunteers who give blood and a few hours of their time to scientists, the project had barely registered on her radar recently. And then last month came a startling discovery. After a chance encounter with the lead scientist, she learned that the research group had published a paper in Science in which her case figured prominently (although only her age at the time of most data collection was listed). The news alarmed her: Researchers suspected that rather than being beneficial, the high HDL Woidislawsky had always been proud of might be deleterious. She had known nothing about the publication plans or her own results. The experience places Woidislawsky at the nexus of two distinct quandaries in clinical research: What health information do researchers owe...