[Perspective] Ionic control of sleep and wakefulness
Thursday, April 28, 2016 - 15:01
in Psychology & Sociology
Brain electrical activity differs markedly between wakefulness and sleep. Concomitant shifts in the ion composition of brain extracellular fluids were thought to be a consequence rather than a cause of the sleep-wake–dependent changes in neuronal activity. On page 550 of this issue, Ding et al. (1) report the surprising observation that ionic changes in the extracellular fluid are a potent control of sleep-wake–dependent neuronal activity. Authors: Hans-Peter Landolt, Sebastian C. Holst