Female chromosomes offer resilience to Alzheimer's

Thursday, August 27, 2020 - 10:20 in Health & Medicine

Women live longer than men with Alzheimer's because their sex chromosomes give them genetic protection from the ravages of the disease. Women get two 'doses' of a gene that only exists on the X chromosome. And some people, both male and female, have an especially potent variant of this gene. Long-term studies of older people, many of whom already had mild cognitive impairment, showed women with one or two copies of the variant progressed more slowly toward Alzheimer's.

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