Diabetes reversed in mice with genetically edited stem cells derived from patients

Friday, April 24, 2020 - 17:11 in Biology & Nature

Researchers have used induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes, transformed the stem cells into insulin-producing cells, used the CRISPR gene-editing tool to correct a defect that caused the diabetes, and implanted the cells into mice to reverse diabetes in the animals.

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