A new mechanism triggering cell death and inflammation: A left turn that kills
Tuesday, March 31, 2020 - 14:30
in Biology & Nature
Researchers describe their discovery of a new mechanism that could contribute to the pathogenesis of inflammatory diseases. The scientists found that ZBP1, a protein best known for defending against incoming viruses, is activated by sensing an unusual form of cellular genetic material (Z-nucleic acids), leading to cell death and inflammation.