Key molecular machine in cells pictured in detail for the first time
Thursday, February 6, 2020 - 17:10
in Biology & Nature
Scientists used biochemical experiments and cryo-electron microscopy (cryo-EM) to determine the atomic structure of a complex assembly of molecules known as the histone mRNA three-prime (3') end-processing machine. This machine plays a fundamental role in proper activity and duplication of the cell genome and when defective, it may lead to human diseases, including cancers.