Scientists simplify and accelerate directed evolution bioengineering method

Sunday, November 11, 2018 - 21:10 in Biology & Nature

Researchers reported that they have accelerated and simplified directed evolution by having live cells do most of the heavy lifting. By inserting a specially engineered DNA replication system into yeast, the scientists were able to coax selected genes to rapidly and stably mutate and evolve as the host yeast cells reproduced.

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