New, rare mechanism for ALL to relapse after CAR T cell therapy
Monday, October 1, 2018 - 16:49
in Physics & Chemistry
A single leukemia cell, unknowingly engineered with the leukemia-targeting chimeric antigen receptor (CAR) lentivirus and infused back into a patient, was able to reproduce and cause a deadly recurrence of B-cell acute lymphoblastic leukemia (ALL).