Ketamine activates opioid system to treat depression
Wednesday, August 29, 2018 - 08:00
in Health & Medicine
A new study finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any antidepressant's mechanism of action. While opioids have been used historically to treat depression, they are known to carry a high risk of dependence.