Stabilizing dysferlin-deficient muscle cell membrane improves muscle function
Monday, August 27, 2018 - 18:10
in Biology & Nature
In a head-to-head trial between the conventional glucocorticoid, prednisolone, and a modified glucocorticoid, vamorolone, in experimental models of LGMD2B, vamorolone improved dysferlin-deficient muscle cell membrane stability and repair. This correlated with increased muscle strength and decreased muscle degeneration, according to a new study.