Combining CAR T cells with existing immunotherapies may overcome resistance in glioblastomas
Wednesday, July 19, 2017 - 22:32
in Health & Medicine
Genetically modified “hunter” T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, researchers report.