Mysterious molecule's function in skin cancer identified
Thursday, May 4, 2017 - 14:52
in Biology & Nature
A researcher has uncovered the M.O. of a mysterious molecule called SPRIGHTLY that acts as a hub for cancer-related genes in the nucleus. The study identified 'major' RNA binding partners -- genes already implicated in a variety of cancers. In a mouse model of melanoma, tumors with reduced SPRIGHTLY grew more slowly, indicating use as a therapeutic target or biomarker.