Estrogen alters memory circuit function in women with gene variant

Tuesday, April 25, 2017 - 14:02 in Psychology & Sociology

Fluctuations in estrogen triggered atypical functioning in a key brain memory circuit in women with a common version of a gene. Brain scans revealed altered circuit activity linked to changes in the sex hormone in women with the gene variant while they performed a working memory task. The findings may help to explain individual differences in risk for, onset, severity, and course of mental disorders, which are often marked by working memory deficits.

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