Surprise finding leads to new insights into splenic B cell differentiation

Friday, February 3, 2017 - 12:01 in Biology & Nature

Researchers are familiar with the functions of MZB cells, but the molecular processes involved in their development remained a mystery until an unrelated test revealed that Taok3 plays an essential role. Using these insights, a research team demonstrated that mice genetically lacking in Taok3 did not develop MZB cells, and are more susceptible to bacterial infection.

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