Defining immortality of stem cells to identify novel anti-aging mechanisms
Monday, November 28, 2016 - 14:01
in Biology & Nature
With age, somatic cells such as neurons lose their ability to maintain the quality of their protein content. Pluripotent stem cells, on the contrary, do not age and have increased mechanism to maintain the integrity of their proteins. Researchers have defined the mechanisms underlying increased protein quality control of pluripotent stem cells. Then, the researchers mimicked these mechanisms in somatic tissues of model organisms to extend lifespan and delay age-related diseases.