Study identifies novel treatment resistance mechanism in BRAF-mutant melanoma
Tuesday, August 9, 2016 - 04:02
in Health & Medicine
A research team has identified an additional mechanism for resistance to targeted treatment for BRAF-mutant melanoma. They report that inactivating mutations in two genes responsible for regulating key aspects of cell division can reactivate the signaling pathway driving tumor growth that had been blocked by BRAF inhibitor drugs.