Guarding the gatekeepers
Monday, May 30, 2016 - 10:41
in Biology & Nature
Calcium is a key signalling agent in the information networks of life. As calcium ions cannot cross cell membranes directly, the rise and fall of calcium levels within a cell are controlled through a set of proteins known as the Orai. Researchers have discovered a new player in calcium signalling pathways - a protein named Septin 7 that functions as a 'molecular brake' to Orai activation.