Rhythm of 'detox' and feeding genes in fruitflies, mice coordinated by neuropeptide
Wednesday, May 18, 2016 - 21:30
in Biology & Nature
A 24-hour rhythm of cellular detoxification in flies and mammals is coordinated by a neuropeptide that also drives feeding in both organisms. Many detoxification genes are expressed with a circadian rhythm in the mouse liver and in the fruitfly equivalent called the fat body. This work could eventually have implications for chronotherapy -- the study of the timing of when best to take medications.