Gene linked to Alzheimer's disease impairs memory by disrupting brain's 'playback system'

Friday, May 6, 2016 - 12:01 in Health & Medicine

Scientists have discovered how the major genetic risk factor for Alzheimer's disease causes memory impairment. A specific type of brain activity important for memory replay is disrupted in mice with the E4 version of the apolipoprotein E (apoE4) gene, which may interfere with memory formation.

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