Parkinson's disease pathogenesis reduced in rat model by a cell-signaling inhibitor drug
Wednesday, May 4, 2016 - 11:21
in Health & Medicine
Researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 -- one of the JAK/STAT pathway inhibitors generally known as Jakinibs -- lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.