Role for oxidized mitochondrial DNA in lupus revealed
Monday, April 18, 2016 - 10:30
in Biology & Nature
The neutrophils of systemic lupus erythematosus patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response, researchers have discovered. The study suggests that targeting the pathways that lead to the accumulation of this DNA and/or facilitate its removal could be new ways to treat this chronic autoimmune disease.