Key switch in the immune system regulated by splicing
Tuesday, April 12, 2016 - 09:30
in Health & Medicine
The protein MALT1 is an important switch in immune cells and affects their activity. Researchers report that this activation is not always equally strong. Through alternative splicing, two variants of the protein may arise which have a stronger or weaker effect on the immune system. Understanding this process is important for the pharmacological use of MALT1.