Scientists find novel metabolic twist that drives cancer survival
Thursday, April 7, 2016 - 14:31
in Biology & Nature
A novel metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal cells has been identified by a team of researchers. The study reveals that cancer cells use an alternate version of two well-known metabolic pathways called the pentose phosphate pathway (PPP) and the Krebs cycle to defend against toxins. The toxins are reactive oxygen species (ROS) that kill cells via oxidative stress.