Lymphoma overrides a key protein's quadruple locks
Tuesday, March 22, 2016 - 09:11
in Biology & Nature
Protein chemists report they are closer to explaining why certain blood cancers are able to crack a molecular security system and run rampant. In a detailed description of their discoveries in lab-grown human cells, the investigators offer evidence that mutations in cancerous lymphoma cells break through not one but four "locks" on the protein CARD11.