Biochemical clues may predict who develops Alzheimer's disease -- and who doesn't

Investigators have wondered why the brains of some cognitively-intact elderly individuals have abundant pathology on autopsy or significant amyloid deposition on neuroimaging that are characteristic of Alzheimer's disease. Researchers haveinvestigated biochemical factors and identified differences in proteins from parietal cortex synapses between patients with and those without manifestation of dementia.

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