Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics
Monday, September 14, 2015 - 09:30
in Biology & Nature
BACE1 is the major drug target for Alzheimer’s disease, but we know surprisingly little about its normal function in the central nervous system (CNS). Researchers now show that this protease is critically involved in axonal guidance processes in thalamic and hippocampal neurons.