iPS cells discover drug target for muscle disease
Thursday, August 20, 2015 - 10:00
in Biology & Nature
Duchenne muscular dystrophy (DMD) is disease that leads to the degeneration of muscle due to dysfunctional expression of the protein dystrophin. A new iPS cell model found that the early stages of DMD development can be attributed to a specific family of ion channels that allows an abnormal influx of calcium to enter the cell. This same model can be used for drug discovery to correct the channel behavior, experts say.