New details of transmission of stimuli in living organisms unveiled

Monday, August 10, 2015 - 11:00 in Biology & Nature

Researchers unveil new details about how cells in a living being process stimuli. The study focuses on so-called G-proteins, which help transmit external stimuli that reach a cell into its interior. Using a technique developed at PSI, the study authors discovered which parts of the G-proteins are vital for their functioning. In particular, they demonstrated that only a few amino acids, protein building blocks, have a major influence on their function. Other amino acids, however, can be altered without compromising their function. The new findings significantly improve our understanding of processes such as sensory perception and hormone activity, and aid the development of new drugs.

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