Gene mutation contributes to liver disease in patients of normal weight
Wednesday, July 22, 2015 - 15:00
in Health & Medicine
Non-alcoholic fatty liver disease (NAFLD) is a major worldwide health problem. The disease is strongly associated with obesity and has been found in a high percentage Asian patients of normal weight. The PNPLA3 mutant genotype has been consistently shown to be a major factor in the development of NAFLD, but the effect of a patient's weight on the relationship between NAFLD and the mutant gene had not been determined until now, at the conclusion of a study on the issue.