Multiple myeloma hides in bones like a wolf in sheep's clothing
Thursday, July 9, 2015 - 16:00
in Biology & Nature
Multiple myeloma uses a trick akin to a wolf in sheep’s clothing to grow in and spread to new bone sites. By overexpressing Runx2, a gene that normally is a master regulator of bone formation, the cells of this largely incurable cancer produce proteins that mimic the normal bone-resident cells.