Research prompts rethink of enzyme evolution

There is a need for a fundamental rethink of the evolutionary path of enzymes, the proteins vital to all life on Earth, new research suggests. Enzymes catalyze a vast array of biologically relevant chemical reactions even in the simplest living cells. Scientists have generally thought of their evolution as events occurring at the molecular level; a smooth and steady trajectory, from barely functional primordial catalysts to the highly active and specific enzymes. However the reality may be quite different.

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