'Missing culprit' in heart failure identified by researchers
Wednesday, March 18, 2015 - 17:00
in Health & Medicine
Working with lab animals and human heart cells, scientists have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. An enzyme called PDE-9 interferes with the body's natural "braking" system needed to neutralize stress on the heart, they report.