Mechanism behind most common form of inherited Alzheimer's disease revealed
Wednesday, March 4, 2015 - 15:50
in Health & Medicine
For the first time, a study reveals exactly how mutations associated with the most common form of inherited Alzheimer's disease produce the disorder's devastating effects. The paper upends conventional thinking about the effects of Alzheimer's-associated mutations in the presenilin genes and provides an explanation for the failure of drugs designed to block presenilin activity.