Confounding factors contribute to unexpected results of trial of renal denervation
Monday, December 8, 2014 - 16:00
in Health & Medicine
A new analysis of an important trial of the blood pressure-lowering procedure, renal denervation, shows that the main results may have been affected by a number of confounding factors that partially explain the unexpected blood pressure responses in patients. The analysis identified factors in the SYMPLICITY HTN-3 trial, such as variations in the way the procedure was performed and changes in patients' medications and drug adherence, which may have had a significant impact on the results.