Unexpected clue to peripheral neuropathies found
Saturday, September 27, 2014 - 05:30
in Biology & Nature
Disrupting the molecular function of a tumor suppressor causes improper formation of a protective insulating sheath on peripheral nerves -- leading to neuropathy and muscle wasting in mice similar to that in human diabetes and neurodegeneration. A new study also suggests that normal molecular function of the tumor suppressor gene Lkb1 is essential to the formation process.