How mutated X-linked mental retardation protein impairs neuron function

Wednesday, June 25, 2014 - 13:20 in Health & Medicine

There are new clues about malfunctions in brain cells that contribute to intellectual disability and possibly other developmental brain disorders. A CSHL team has discovered how defects in an X-linked mental retardation protein, OPHN1, can lead to impairments in the maturation and adjustment of synaptic strength of excitatory neurons in the brain.

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