Mechanism discovered for attaching an 'on' switch that helps cells accessorize proteins

Thursday, June 19, 2014 - 20:30 in Biology & Nature

Scientists have discovered how an important “on” switch is attached to the machinery that cells rely on to adapt thousands of proteins to meet changing conditions. The switch is a small protein called NEDD8. Problems with NEDD8 have been associated with several cancers, developmental disorders and infectivity of the human immunodeficiency virus (HIV), which causes AIDS.

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