Melatonin makes old bones stronger, research shows

Melatonin supplements may make bones stronger in old rats, research shows. This suggests a possible avenue for the prevention of osteoporosis. Bones are built up by certain cells known as osteoblasts during the daytime and broken down by others (osteoclasts) at night. As we age, we sleep less, and so the cells that break down the bones are more active. By giving old rats melatonin supplements to regulate their circadian rhythms, the researchers have been able to make their bones denser, less brittle and more flexible.

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