The promise of purple for enhanced bioimaging

Newly detected ‘energy-clustering’ structures inside rare-earth nanoparticles generate intense violet light, which is ideal for studying photon-induced transformations. Labeling biomolecules with light-emitting nanoparticles is a powerful technique for observing cell movement and signaling under realistic, in vivo conditions. The small size of these probes, however, often limits their optical capabilities. In particular, many nanoparticles have trouble producing high-energy light with wavelengths in the violet to ultraviolet range, which can trigger critical biological reactions.

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