Proteins conspire to make breast cancer cells resistant to drug treatment
Sunday, April 20, 2014 - 12:31
in Health & Medicine
The interaction between two proteins called BCAR1 and BCAR3 is responsible for resistance to antiestrogen drugs, paving the way for improved diagnostic and treatment strategies. “Drug resistance is one of the most serious obstacles to breast cancer eradication,” said the senior study author. “Our findings suggest that strategies to disrupt the BCAR1-BCAR3 complex and associated signaling networks could potentially overcome this obstacle and ultimately lead to more-effective breast cancer therapies.”