Combination ARV vaginal ring to prevent HIV safe in trial but 1 ARV carries the weight, study suggests

Wednesday, March 5, 2014 - 08:31 in Health & Medicine

An early phase clinical trial of a vaginal ring containing the antiretroviral (ARV) drugs dapivirine and maraviroc found the ring was safe in women who wore it for 28 days and evidence of dapivirine in cervical tissue and blood. In addition, laboratory tests of tissue samples showed that dapivirine was able to block HIV infection, though levels of maraviroc were not sufficient to have a similar effect, report researchers.

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