New biological mechanisms, treatment paradigm for kidney disease

Tuesday, March 4, 2014 - 08:00 in Health & Medicine

Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research has uncovered abnormal molecular signaling pathways from disease initiation to irreversible kidney damage, kidney failure, and death.

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