Research reveals structure of master regulator, new drug target for autism, cervical cancer
Friday, January 10, 2014 - 11:30
in Biology & Nature
A team of scientists has discovered the structure of the active form of E6-associated protein (E6AP), an enzyme that acts as a master regulator, controlling functions like the ability of nerve cells to "rewire" themselves in response to external stimuli and HPV hijacking cells leading to cervical cancer. They report, for the first time, that the active form of E6AP is composed of three distinct protein molecules.