Mechanism of genetic mutations known to cause familial Alzheimer's disease uncovered
Friday, January 10, 2014 - 13:30
in Biology & Nature
New research has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. Researchers followed the trail of two genetic mutations – V44M and V44A – known to cause FAD, and have shown how the mutations lead to biochemical changes long linked to the disease.