New method for efficiently transporting antibodies across the blood-brain barrier
Wednesday, January 8, 2014 - 13:00
in Biology & Nature
Researchers have published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models. Scientists found that such enhanced transfer of antibodies through the BBB was associated with a marked improvement in amyloid reduction in the brain of a mouse model of Alzheimer’s disease.