Overworked cellular machines may explain Gaucher disease link to Parkinson's disease
Wednesday, December 18, 2013 - 10:36
in Biology & Nature
Research with fruit fly model suggests that Gaucher disease (GD) is related to Parkinson's disease (PD) through biological pathways triggered by accumulated defective proteins related to GD. Accumulation, due to overworked cellular machines responsible for degrading defective proteins, triggers cascade that leads to the death of dopamine-producing cells that causes PD.