Protein surfaces defects act as drug targets
Tuesday, July 30, 2013 - 12:30
in Biology & Nature
New research shows a physical characterization of the interface of the body's proteins with water. Identifying the locations where it is easiest to remove water from the interface of target proteins could constitute a novel drug design strategy. The candidate drugs would need to be engineered to bind at the site of the protein where interfacial water is most easily dislodged.